FD ISO/TR 14735

FD ISO/TR 14735

July 2013
Published document Current

Cosmetics - Analytical methods - Nitrosamines : technical guidance document for minimising and determining N-nitrosamines in cosmetics

ISO/TR 14735:2013 aims to contribute to providing general advice on strategies that can be adopted to minimize the likelihood of N-nitrosamine formation in cosmetic products and provide a description of the analytical methodologies available for the reliable determination of N-nitrosamines in cosmetic products. It also seeks to provide some insight into the relevance and limitations of each of the methods described and finally provide an analytical approach for the analysis of N-nitrosamines in cosmetic products and raw materials. ISO/TR 14735:2013 covers the reduction or elimination of adventitious nitrite sources, reduction or elimination of secondary amino sources, incorporation of inhibitors to N-nitrosamine formation and analytical methodologies for total N-nitroso compounds and specific methods for N-nitrosodiethanolamine (NDELA).

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Main informations

Collections

National standards and national normative documents

Publication date

July 2013

Number of pages

18 p.

Reference

FD ISO/TR 14735

ICS Codes

71.100.70   Cosmetics. Toiletries

Classification index

T75-637

Print number

1 - 02/08/2013

International kinship

ISO/TR 14735:2013
Sumary
Cosmetics - Analytical methods - Nitrosamines : technical guidance document for minimising and determining N-nitrosamines in cosmetics

ISO/TR 14735:2013 aims to contribute to providing general advice on strategies that can be adopted to minimize the likelihood of N-nitrosamine formation in cosmetic products and provide a description of the analytical methodologies available for the reliable determination of N-nitrosamines in cosmetic products. It also seeks to provide some insight into the relevance and limitations of each of the methods described and finally provide an analytical approach for the analysis of N-nitrosamines in cosmetic products and raw materials.

ISO/TR 14735:2013 covers the reduction or elimination of adventitious nitrite sources, reduction or elimination of secondary amino sources, incorporation of inhibitors to N-nitrosamine formation and analytical methodologies for total N-nitroso compounds and specific methods for N-nitrosodiethanolamine (NDELA).

Table of contents
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  • Avant-propos
    iv
  • Introduction
    v
  • 1 Domaine d'application
    1
  • 2 Composition chimique des N-nitrosamines
    1
  • 3 Stratégies de limitation
    1
  • 3.1 Réduction ou élimination des sources accidentelles de nitrite
    1
  • 3.2 Réduction ou élimination des sources de composés amines secondaires
    2
  • 3.3 Incorporation d'inhibiteurs de la formation de nitrosamines
    2
  • 3.4 Traitement potentiel des matières premières cosmétiques pour la décomposition des N-nitrosamines
    3
  • 4 Méthodes analytiques
    3
  • 4.1 Recherche des composés N-nitrosés dans les produits cosmétiques par détection chimiluminescente de l'oxyde nitrique
    3
  • 4.2 Teneur apparente en nitrosamines totales (TANT)
    3
  • 4.3 Méthodes relatives à la NDELA
    4
  • 4.4 Détermination d'autres N-nitrosamines spécifiques
    5
  • 5 Approche analytique
    5
  • 5.1 Généralités
    5
  • 5.2 Screening
    5
  • 5.3 Mesurage de N-nitrosamines spécifiques
    6
  • Annexe A (informative) Composés référencés comme inhibiteurs
    8
  • Bibliographie
    9
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