NF ISO 10130

NF ISO 10130

February 2010
Standard Current

Cosmetics - Analytical methods - Nitrosamines : detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC, post-column photolysis and derivitization

ISO 10130:2009 describes a method for the detection and quantification of N‑nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics by High Performance Liquid Chromatography (HPLC) coupled with post-column photolysis and derivatization.This method is not applicable to the detection and/or quantification of nitrosamines other than NDELA, nor to the detection and/or quantification of NDELA in products other than cosmetics or raw materials used in cosmetics.If a product has the possibility of either NDELA contamination from the ingredients or NDELA formation by the composition of ingredients, the method will be applied for the testing of cosmetic products and is an alternative to ISO 15819.This method is not applicable to matrices containing oxidation dyes.

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Main informations

Collections

National standards and national normative documents

Publication date

February 2010

Number of pages

20 p.

Reference

NF ISO 10130

ICS Codes

71.100.70   Cosmetics. Toiletries

Classification index

T75-632

Print number

1 - 16/02/2010

International kinship

ISO 10130:2009
Sumary
Cosmetics - Analytical methods - Nitrosamines : detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC, post-column photolysis and derivitization

ISO 10130:2009 describes a method for the detection and quantification of N‑nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics by High Performance Liquid Chromatography (HPLC) coupled with post-column photolysis and derivatization.

This method is not applicable to the detection and/or quantification of nitrosamines other than NDELA, nor to the detection and/or quantification of NDELA in products other than cosmetics or raw materials used in cosmetics.

If a product has the possibility of either NDELA contamination from the ingredients or NDELA formation by the composition of ingredients, the method will be applied for the testing of cosmetic products and is an alternative to ISO 15819.

This method is not applicable to matrices containing oxidation dyes.

Table of contents
  • Avant-propos
    iv
  • Introduction
    v
  • 1 Domaine d'application
    1
  • 2 Principe
    1
  • 3 Réactifs
    1
  • 4 Appareillage
    2
  • 5 Préparation et conservation des échantillons
    4
  • 5.1 Généralités
    4
  • 5.2 Préparation des étalons
    4
  • 5.3 Préparation des échantillons
    5
  • 6 Mode opératoire
    6
  • 6.1 Généralités
    6
  • 6.2 Conditions chromatographiques
    6
  • 6.3 Installation du système de réaction
    6
  • 7 Calcul des résultats
    7
  • 7.1 Courbe d'étalonnage
    7
  • 7.2 Conditions expérimentales de validité du mesurage
    7
  • 7.3 Calcul des concentrations
    7
  • 8 Rapport d'essai
    8
  • Annexe A (informative) Exemples de courbe d'étalonnage et de chromatogrammes
    9
  • Annexe B (normative) Photolyse et réaction du nitrite au réactif de Griess jusqu'à formation du colorant azoïque
    12
  • Annexe C (normative) Configuration du système de réacteur post-colonne
    13
  • Bibliographie
    14
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