NF ISO 19290

NF ISO 19290

January 2017
Standard Cancelled

Cigarettes - Determination of tobacco specific nitrosamines in mainstream cigarette smoke - Method using LC-MS/MS

ISO 19290:2016 specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

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Main informations

Collections

National standards and national normative documents

Publication date

January 2017

Number of pages

23 p.

Reference

NF ISO 19290

ICS Codes

65.160   Tobacco, tobacco products and related equipment

Classification index

V37-199

Print number

1

International kinship

ISO 19290:2016
Sumary
Cigarettes - Determination of tobacco specific nitrosamines in mainstream cigarette smoke - Method using LC-MS/MS

ISO 19290:2016 specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Standard replaced by (1)
NF ISO 19290
October 2021
Standard Current
Cigarettes - Determination of tobacco specific nitrosamines in mainstream cigarette smoke - Method using LC-MS/MS

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Table of contents
  • 1 Domaine d'application
  • 2 Références normatives
  • 3 Termes et définitions
  • 4 Principe
  • 5 Appareillage
  • 6 Réactifs
  • 7 Préparation
  • 8 Échantillonnage
  • 9 Préparation du produit du tabac
  • 10 Production de l'échantillon - Fumage de cigarettes
  • 11 Analyse de l'échantillon
  • 12 Répétabilité et reproductibilité
  • 13 Rapport d'essai
  • Annexe A Exemples de chromatogrammes types
  • Bibliographie
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